› 3f1r

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192468 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 20 Chains: A, B
Molecule details ›
Chains: A, B
Length: 211 amino acids
Theoretical weight: 23.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NP95 (Residues: 1-211; Coverage: 100%)
Gene name: FGF20
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

1 bound ligand:
Ligand SO4 6 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: R3
Unit cell:
a: 102.144Å b: 102.144Å c: 119.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.256 0.256 0.273
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease.
Itoh et al. (2011)
11 more

3 mentions without citation

Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification.
Li et al. (2016)
2 more