3f2u

X-ray diffraction
1.8Å resolution

Crystal structure of human chromobox homolog 1 (CBX1)

Released:
Source organism: Homo sapiens
Entry authors: Amaya MF, Ravichandran M, Tempel W, Wernimont AK, Loppnau P, Kozieradzki I, Edwards AM, Arrowsmith CH, Weigelt J, Bountra C, Botchkarev A, Min J, Ouyang H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-160771 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromobox protein homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 55 amino acids
Theoretical weight: 6.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P83916 (Residues: 20-73; Coverage: 29%)
Gene names: CBX, CBX1
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: C2
Unit cell:
a: 51.057Å b: 39.068Å c: 37.832Å
α: 90° β: 137.03° γ: 90°
R-values:
R R work R free
0.224 0.222 0.274
Expression system: Escherichia coli