› 3f3q

X-ray diffraction
1.76Å resolution

Crystal structure of the oxidised form of thioredoxin 1 from saccharomyces cerevisiae

Released:
DOI: 10.2210/pdb3f3q/pdb
PDB entry 3f3q coloured by chain, front view.
PDB entry 3f3q coloured by chain, side view.
PDB entry 3f3q coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural and kinetic analysis of Saccharomyces cerevisiae thioredoxin Trx1: implications for the catalytic mechanism of GSSG reduced by the thioredoxin system.
Bao R, Zhang Y, Lou X, Zhou CZ, Chen Y
Biochim Biophys Acta 1794 1218-23 (2009)
PMID: 19362171

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149546 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-1 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.07 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P22217 (Residues: 1-103; Coverage: 100%)
Gene names: TRX1, TRX2, YLR043C
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand ZN 3 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 32.292Å b: 46.588Å c: 64.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.245
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Thioredoxin and glutaredoxin systems in plants: molecular mechanisms, crosstalks, and functional significance.
Meyer et al. (2012)
1 more

2 mentions without citation

Auto-encoding NMR chemical shifts from their native vector space to a residue-level biophysical index.
Orlando et al. (2019)
1 more