› 3f45

X-ray diffraction
2Å resolution

Structure of the R75A mutant of rat alpha-Parvalbumin

Released:
DOI: 10.2210/pdb3f45/pdb
PDB entry 3f45 coloured by chain, front view.
PDB entry 3f45 coloured by chain, side view.
PDB entry 3f45 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Removing the invariant salt bridge of parvalbumin increases flexibility in the AB-loop structure.
Hoh F, Cavé A, Strub MP, Banères JL, Padilla A
Acta Crystallogr D Biol Crystallogr 65 733-43 (2009)
PMID: 19622856

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135966 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Parvalbumin alpha Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 11.73 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P02625 (Residues: 2-110; Coverage: 99%)
Gene names: Pva, Pvalb
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 27.315Å b: 55.05Å c: 28.768Å
α: 90° β: 105.56° γ: 90°
R-values:
R R work R free
0.158 0.144 0.205
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

Comprehensive Sequence Analysis of Parvalbumins in Fish and Their Comparison with Parvalbumins in Tetrapod Species.
Dijkstra et al. (2022)