› 3f6f

X-ray diffraction
1.6Å resolution

Crystal Structure of Glutathione Transferase dmGSTD10 from Drosophila melanogaster

Released:
DOI: 10.2210/pdb3f6f/pdb
PDB entry 3f6f coloured by chain, front view.
PDB entry 3f6f coloured by chain, side view.
PDB entry 3f6f coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structural evidence for conformational changes of Delta class glutathione transferases after ligand binding.
Wongsantichon J, Robinson RC, Ketterman AJ
Arch Biochem Biophys 521 77-83 (2012)
PMID: 22475449

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
IP02193p Chain: A
Molecule details ›
Chain: A
Length: 210 amino acids
Theoretical weight: 24.62 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9VGA1 (Residues: 1-210; Coverage: 100%)
Gene names: CG17392, CG18548, DmGSTD10, Dmel\CG18548, Dmel_CG18548, GSTD10, GstD10, gstd10
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P4122
Unit cell:
a: 49.649Å b: 49.649Å c: 195.373Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.219
Expression system: Escherichia coli

Quick links

Citations

6 citation in other articles

Mechanistic studies of FosB: a divalent-metal-dependent bacillithiol-S-transferase that mediates fosfomycin resistance in Staphylococcus aureus.
Roberts et al. (2013)
5 more

3 mentions without citation

Antenna-specific glutathione S-transferase in male silkmoth Bombyx mori.
Tan et al. (2014)
2 more