› 3f85

X-ray diffraction
2.1Å resolution

Structure of fusion complex of homo trimeric major pilin subunits CfaB of CFA/I fimbirae from ETEC E. coli

Released:
DOI: 10.2210/pdb3f85/pdb
PDB entry 3f85 coloured by chain, front view.
PDB entry 3f85 coloured by chain, side view.
PDB entry 3f85 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Structure of CFA/I fimbriae from enterotoxigenic Escherichia coli.
Li YF, Poole S, Nishio K, Jang K, Rasulova F, McVeigh A, Savarino SJ, Xia D, Bullitt E
Proc Natl Acad Sci U S A 106 10793-8 (2009)
PMID: 19515814

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-122890 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CFA/I fimbrial subunit B Chain: A
Molecule details ›
Chain: A
Length: 463 amino acids
Theoretical weight: 47.99 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: E3PPC4 (Residues: 37-170, 24-170, 24-38; Coverage: 100%)
Gene names: ETEC_p948_0400, cfaB
Structure domains: CFA/I fimbrial subunit E, pilin domain

Ligands and Environments

1 bound ligand:
Ligand MG 4 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2
Unit cell:
a: 127.406Å b: 44.982Å c: 97.88Å
α: 90° β: 125.35° γ: 90°
R-values:
R R work R free
0.236 0.233 0.283
Expression system: Escherichia coli

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Citations

6 review citations

The type II secretion system: biogenesis, molecular architecture and mechanism.
Korotkov et al. (2012)
5 more

4 mentions without citation

Structure of CFA/I fimbriae from enterotoxigenic Escherichia coli.
Li et al. (2009)
3 more