› 3fod

X-ray diffraction
1.4Å resolution

AILSST segment from Islet Amyloid Polypeptide

Released:
DOI: 10.2210/pdb3fod/pdb
PDB entry 3fod coloured by chain, front view.
PDB entry 3fod coloured by chain, side view.
PDB entry 3fod coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Molecular mechanisms for protein-encoded inheritance.
Wiltzius JJ, Landau M, Nelson R, Sawaya MR, Apostol MI, Goldschmidt L, Soriaga AB, Cascio D, Rajashankar K, Eisenberg D
Nat Struct Mol Biol 16 973-8 (2009)
PMID: 19684598

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163560 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AILSST hexapeptide segment from Islet Amyloid Polypeptide Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 6 amino acids
Theoretical weight: 591 Da
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 9.542Å b: 86.654Å c: 19.482Å
α: 90° β: 90.01° γ: 90°
R-values:
R R work R free
0.226 0.222 0.265
Expression system: Not provided

Quick links

Citations

39 review citations

The amyloid state of proteins in human diseases.
Eisenberg et al. (2012)
38 more

10 mentions without citation

Ubiquitous amyloids.
Pulawski et al. (2012)
9 more