Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Hydrolysis of four peptide bonds in the viral precursor polyprotein, commonly with Asp or Glu in the P6 position, Cys or Thr in P1 and Ser or Ala in P1'.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Non-structural protein 5A (preferred)
PDBe Complex ID:
PDB-CPX-194374 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 5A
Molecule details ›
Chains: A, B
Length: 177 amino acids
Theoretical weight: 19.47 KDa
Source organism: Hepatitis C virus (isolate Con1)
Expression system: Escherichia coli
UniProt:
Length: 177 amino acids
Theoretical weight: 19.47 KDa
Source organism: Hepatitis C virus (isolate Con1)
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9WMX2 (Residues: 2005-2174; Coverage: 6%)
- Hepatitis C virus non-structural 5a zinc finger domain
- Hepatitis C virus non-structural 5a domain 1b
