› 3fwo

X-ray diffraction
3.71Å resolution

The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin

Released:
DOI: 10.2210/pdb3fwo/pdb
PDB entry 3fwo coloured by chain, front view.
PDB entry 3fwo coloured by chain, side view.
PDB entry 3fwo coloured by chain, top view.
Source organism: Deinococcus radiodurans R1
Primary publication:
Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin
Auerbach T, Mermershtain I, Bashan A, Davidovich C, Rozenberg H, Sherman DH, Yonath A
Biotechnologia 1 24-35 (2009)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-195821 (preferred)
Entry contents:
2 distinct RNA molecules
Macromolecules (2 distinct):
23S ribosomal RNA Chain: A
Molecule details ›
Chain: A
Length: 2880 nucleotides
Theoretical weight: 933.41 KDa
Source organism: Deinococcus radiodurans R1
Sequence domains: Bacterial large subunit ribosomal RNA
5S ribosomal RNA Chain: B
Molecule details ›
Chain: B
Length: 118 nucleotides
Theoretical weight: 38.03 KDa
Source organism: Deinococcus radiodurans R1
Sequence domains: 5S ribosomal RNA

Ligands and Environments

1 bound ligand:
Ligand MT9 1 x MT9
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2, ESRF BEAMLINE ID23-1
Spacegroup: I222
Unit cell:
a: 172.499Å b: 415.691Å c: 701.729Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.278 0.278 0.337

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