› 3g17

X-ray diffraction
2.3Å resolution

Structure of putative 2-dehydropantoate 2-reductase from staphylococcus aureus

Released:
DOI: 10.2210/pdb3g17/pdb
PDB entry 3g17 coloured by chain, front view.
PDB entry 3g17 coloured by chain, side view.
PDB entry 3g17 coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus Mu50
Entry authors: Ramagopal UA, Toro R, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102027 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-dehydropantoate 2-reductase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 294 amino acids
Theoretical weight: 33.44 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3K174 (Residues: 2-285; Coverage: 99%)
Gene name: SAV2600
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P1
Unit cell:
a: 75.239Å b: 99.64Å c: 100.261Å
α: 103.66° β: 105.23° γ: 102.26°
R-values:
R R work R free
0.203 0.2 0.26
Expression system: Escherichia coli

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