3g7t

X-ray diffraction
3.5Å resolution

Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation

Released:

Function and Biology Details

Reactions catalysed:
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179325 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope protein Chain: A
Molecule details ›
Chain: A
Length: 400 amino acids
Theoretical weight: 43.75 KDa
Source organism: Dengue virus 1
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q689G3 (Residues: 281-680; Coverage: 12%)
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C, NSLS BEAMLINE X25
Spacegroup: P6322
Unit cell:
a: 75.65Å b: 75.65Å c: 292.802Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.208 0.297
Expression system: Drosophila melanogaster