› 3gec

X-ray diffraction
4Å resolution

Crystal structure of a tandem PAS domain fragment of Drosophila PERIOD

Released:
DOI: 10.2210/pdb3gec/pdb
PDB entry 3gec coloured by chain, front view.
PDB entry 3gec coloured by chain, side view.
PDB entry 3gec coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structural and functional analyses of PAS domain interactions of the clock proteins Drosophila PERIOD and mouse PERIOD2.
Hennig S, Strauss HM, Vanselow K, Yildiz O, Schulze S, Arens J, Kramer A, Wolf E
PLoS Biol 7 e94 (2009)
PMID: 19402751

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139686 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Period circadian protein Chain: A
Molecule details ›
Chain: A
Length: 312 amino acids
Theoretical weight: 34.94 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07663 (Residues: 232-538; Coverage: 25%)
Gene names: CG2647, per
Sequence domains:
Structure domains: PAS domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P3221
Unit cell:
a: 114.95Å b: 114.95Å c: 85.7Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.247 0.244 0.312
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

17 review citations

Circadian Oscillators: Around the Transcription-Translation Feedback Loop and on to Output.
Hurley et al. (2016)
16 more

2 mentions without citation

Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain.
Wu et al. (2013)
1 more