3ghy

X-ray diffraction
2Å resolution

Crystal structure of a putative ketopantoate reductase from Ralstonia solanacearum MolK2

Released:
Source organism: Ralstonia solanacearum MolK2
Entry authors: Patskovsky Y, Ramagopal UA, Toro R, Morano C, Freeman J, Chang S, Sauder JM, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed:
(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
PDBe Complex ID:
PDB-CPX-123606 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-dehydropantoate 2-reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 335 amino acids
Theoretical weight: 34.99 KDa
Source organism: Ralstonia solanacearum MolK2
Expression system: Escherichia coli
UniProt:
  • Canonical: F6G5W7 (Residues: 44-367; Coverage: 88%)
Gene names: RSPO_c00079, apbA
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P43
Unit cell:
a: 70.648Å b: 70.648Å c: 145.409Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.231 0.278
Expression system: Escherichia coli