› 3glj

X-ray diffraction
1.89Å resolution

A polymorph of carboxypeptidase B zymogen structure

Released:
DOI: 10.2210/pdb3glj/pdb
Model geometry
Fit model/data
PDB entry 3glj coloured by chain, front view.
PDB entry 3glj coloured by chain, side view.
PDB entry 3glj coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Analysis of a new crystal form of procarboxypeptidase B: further insights into the catalytic mechanism.
Fernández D, Boix E, Pallarès I, Avilés FX, Vendrell J
Biopolymers 93 178-85 (2010)
PMID: 19802820

Function and Biology Details

Reaction catalysed: 
Preferential release of a C-terminal lysine or arginine amino acid.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140836 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carboxypeptidase B Chain: A
Molecule details ›
Chain: A
Length: 401 amino acids
Theoretical weight: 45.89 KDa
Source organism: Sus scrofa
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P09955 (Residues: 16-416; Coverage: 100%)
Gene names: CPB, CPB1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand GOL 5 x GOL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P1
Unit cell:
a: 49.59Å b: 49.97Å c: 50.63Å
α: 109.94° β: 104.5° γ: 96.19°
R-values:
R R work R free
0.166 0.166 0.198
Expression system: Komagataella pastoris

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Citations

2 review citations

Progress in metallocarboxypeptidases and their small molecular weight inhibitors.
Fernández et al. (2010)
1 more