› 3gqq

X-ray diffraction
1.94Å resolution

Crystal structure of the human retinal protein 4 (unc-119 homolog A). Northeast Structural Genomics Consortium target HR3066a

Released:
DOI: 10.2210/pdb3gqq/pdb
PDB entry 3gqq coloured by chain, front view.
PDB entry 3gqq coloured by chain, side view.
PDB entry 3gqq coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vorobiev SM, Chen Y, Seetharaman J, Shastry R, Foote EL, Ciccosanti C, Sahdev S, Xiao R, Acton TB, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171686 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein unc-119 homolog A Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 195 amino acids
Theoretical weight: 23.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13432 (Residues: 56-240; Coverage: 77%)
Gene names: RG4, UNC119
Sequence domains: GMP-PDE, delta subunit
Structure domains: GMP phosphodiesterase, delta subunit

Ligands and Environments

1 bound ligand:
Ligand UNL 30 x UNL
1 modified residue:
Ligand MSE 30 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P212121
Unit cell:
a: 77.888Å b: 79.56Å c: 189.717Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.191 0.214
Expression system: Escherichia coli

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