› 3gse

X-ray diffraction
2.28Å resolution

Crystal structure of menaquinone-specific isochorismate synthase from Yersinia pestis CO92

Released:
DOI: 10.2210/pdb3gse/pdb
PDB entry 3gse coloured by chain, front view.
PDB entry 3gse coloured by chain, side view.
PDB entry 3gse coloured by chain, top view.
Source organism: Yersinia pestis
Entry authors: Nocek B, Gu M, Papazisi L, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
Chorismate = isochorismate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184033 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Isochorismate synthase MenF Chain: A
Molecule details ›
Chain: A
Length: 458 amino acids
Theoretical weight: 51.32 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8D0S5 (Residues: 3-457; Coverage: 100%)
Gene names: YP_2339, menF, y1659
Sequence domains: chorismate binding enzyme
Structure domains: Anthranilate synthase

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: C2
Unit cell:
a: 84.19Å b: 76.997Å c: 70.414Å
α: 90° β: 90.39° γ: 90°
R-values:
R R work R free
0.196 0.193 0.252
Expression system: Escherichia coli

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