› 3h1m

X-ray diffraction
2.5Å resolution

Crystal structure of mannose 6-phosphate isomerase (holo; zinc bound)

Released:
DOI: 10.2210/pdb3h1m/pdb
PDB entry 3h1m coloured by chain, front view.
PDB entry 3h1m coloured by chain, side view.
PDB entry 3h1m coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Entry authors: Sagurthi SR, Giri G, Savithri HS, Murthy MRN

Function and Biology Details

Reaction catalysed: 
D-mannose 6-phosphate = D-fructose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150365 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mannose-6-phosphate isomerase Chain: A
Molecule details ›
Chain: A
Length: 393 amino acids
Theoretical weight: 42.79 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
UniProt:
  • Canonical: P25081 (Residues: 1-391; Coverage: 100%)
Gene names: STM1467, manA, pmi
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand EDO 3 x EDO
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 36.03Å b: 92.46Å c: 111.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.188 0.232
Expression system: Escherichia coli

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