› 3he4

X-ray diffraction
2.46Å resolution

Heterospecific coiled-coil pair SYNZIP5:SYNZIP6

Released:
DOI: 10.2210/pdb3he4/pdb
PDB entry 3he4 coloured by chain, front view.
PDB entry 3he4 coloured by chain, side view.
PDB entry 3he4 coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
A synthetic coiled-coil interactome provides heterospecific modules for molecular engineering.
Reinke AW, Grant RA, Keating AE
J Am Chem Soc 132 6025-31 (2010)
PMID: 20387835

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dodecamer
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163621 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SYNZIP6 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 56 amino acids
Theoretical weight: 6.36 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
SYNZIP5 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 46 amino acids
Theoretical weight: 5.44 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P63
Unit cell:
a: 82.678Å b: 82.678Å c: 150.545Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.212 0.258
Expression system: Escherichia coli

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Citations

18 review citations

The coming of age of de novo protein design.
Huang et al. (2016)
17 more

7 mentions without citation

A synthetic coiled-coil interactome provides heterospecific modules for molecular engineering.
Reinke et al. (2010)
6 more