› 3hj4

X-ray diffraction
1.56Å resolution

Function and Biology Details

Reaction catalysed: 
UTP + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111670 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Terminal uridylyltransferase 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 384 amino acids
Theoretical weight: 44.82 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli
UniProt:
  • Canonical: C7AJA4 (Residues: 3-385; Coverage: 94%)
Gene name: MEAT1
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 26 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 63.208Å b: 102.027Å c: 66.074Å
α: 90° β: 111.99° γ: 90°
R-values:
R R work R free
0.164 0.162 0.203
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Uridine insertion/deletion editing in trypanosomes: a playground for RNA-guided information transfer.
Aphasizhev et al. (2011)
6 more

1 mention without citation

Structure of the mitochondrial editosome-like complex associated TUTase 1 reveals divergent mechanisms of UTP selection and domain organization.
Stagno et al. (2010)