› 3hjv

X-ray diffraction
1.7Å resolution

1.7 Angstrom resolution crystal structure of an acyl carrier protein S-malonyltransferase from Vibrio cholerae O1 biovar eltor str. N16961

Released:
DOI: 10.2210/pdb3hjv/pdb
PDB entry 3hjv coloured by chain, front view.
PDB entry 3hjv coloured by chain, side view.
PDB entry 3hjv coloured by chain, top view.
Source organism: Vibrio cholerae
Entry authors: Halavaty AS, Wawrzak Z, Anderson S, Skarina T, Onopriyenko O, Kwon K, Savchenko A, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192032 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Malonyl CoA-acyl carrier protein transacylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 312 amino acids
Theoretical weight: 33.62 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9KQH6 (Residues: 1-312; Coverage: 100%)
Gene name: VC_2022
Sequence domains: Acyl transferase domain
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand SO4 18 x SO4
Ligand CXS 6 x CXS
Ligand CL 9 x CL
Ligand 8JZ 1 x 8JZ
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 46.525Å b: 87.789Å c: 121.957Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.148 0.145 0.193
Expression system: Escherichia coli

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