› 3hoe

X-ray diffraction
2.3Å resolution

Crystal Structure of Surface Lipoprotein

Released:
DOI: 10.2210/pdb3hoe/pdb
PDB entry 3hoe coloured by chain, front view.
PDB entry 3hoe coloured by chain, side view.
PDB entry 3hoe coloured by chain, top view.
Source organism: Actinobacillus pleuropneumoniae
Primary publication:
Insights into the bacterial transferrin receptor: the structure of transferrin-binding protein B from Actinobacillus pleuropneumoniae.
Moraes TF, Yu RH, Strynadka NC, Schryvers AB
Mol Cell 35 523-33 (2009)
PMID: 19716795

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175008 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transferrin-binding protein B Chains: A, B
Molecule details ›
Chains: A, B
Length: 255 amino acids
Theoretical weight: 28.1 KDa
Source organism: Actinobacillus pleuropneumoniae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q44124 (Residues: 56-308; Coverage: 46%)
Gene name: tbpB
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2
Unit cell:
a: 142.473Å b: 43.431Å c: 100.397Å
α: 90° β: 118.16° γ: 90°
R-values:
R R work R free
0.198 0.194 0.261
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Transition Metals and Virulence in Bacteria.
Palmer et al. (2016)
12 more

3 mentions without citation

Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities.
Frandoloso et al. (2015)
2 more