› 3hse

X-ray diffraction
2.9Å resolution

Crystal structure of Staphylococcus aureus protein SarZ in reduced form

Released:
DOI: 10.2210/pdb3hse/pdb
PDB entry 3hse coloured by chain, front view.
PDB entry 3hse coloured by chain, side view.
PDB entry 3hse coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus str. Newman
Primary publication:
Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus.
Poor CB, Chen PR, Duguid E, Rice PA, He C
J Biol Chem 284 23517-24 (2009)
PMID: 19586910

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MarR family regulatory protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 140 amino acids
Theoretical weight: 16.41 KDa
Source organism: Staphylococcus aureus subsp. aureus str. Newman
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3KA72 (Residues: 7-142; Coverage: 92%)
Gene name: NWMN_2286
Sequence domains: MarR family
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P4122
Unit cell:
a: 60.83Å b: 60.83Å c: 192.81Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.286 0.286 0.317
Expression system: Escherichia coli

Quick links

Citations

22 review citations

Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery.
Paulsen et al. (2013)
21 more

6 mentions without citation

From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence?
Priest et al. (2012)
5 more