› 3hz8

X-ray diffraction
1.45Å resolution

Crystal structure of the oxidized T176V DsbA1 mutant

Released:
DOI: 10.2210/pdb3hz8/pdb
PDB entry 3hz8 coloured by chain, front view.
PDB entry 3hz8 coloured by chain, side view.
PDB entry 3hz8 coloured by chain, top view.
Source organism: Neisseria meningitidis MC58
Primary publication:
Biochemical and structural study of the homologues of the thiol-disulfide oxidoreductase DsbA in Neisseria meningitidis.
Lafaye C, Iwema T, Carpentier P, Jullian-Binard C, Kroll JS, Collet JF, Serre L
J Mol Biol 392 952-66 (2009)
PMID: 19631659

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191738 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 193 amino acids
Theoretical weight: 21.51 KDa
Source organism: Neisseria meningitidis MC58
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K189 (Residues: 41-232; Coverage: 89%)
Gene names: NMB0278, dsbA-1
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P212121
Unit cell:
a: 44.307Å b: 47.615Å c: 79.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.191 0.226
Expression system: Escherichia coli

Quick links

Citations

11 review citations

How proteins form disulfide bonds.
Depuydt et al. (2011)
10 more

5 mentions without citation

The Order-Disorder Continuum: Linking Predictions of Protein Structure and Disorder through Molecular Simulation.
Hsu et al. (2020)
4 more