› 3hzj

X-ray diffraction
2.3Å resolution

Crystal structure of the RabGAP domain of the RABGAP1L protein

Released:
DOI: 10.2210/pdb3hzj/pdb
PDB entry 3hzj coloured by chain, front view.
PDB entry 3hzj coloured by chain, side view.
PDB entry 3hzj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Nedyalkova L, Tempel W, Tong Y, Zhong N, MacKenzie F, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177776 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rab GTPase-activating protein 1-like Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 310 amino acids
Theoretical weight: 36.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5R372 (Residues: 507-815; Coverage: 38%)
Gene names: HHL, KIAA0471, RABGAP1L
Sequence domains: Rab-GTPase-TBC domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand UNX 32 x UNX
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P212121
Unit cell:
a: 48.086Å b: 64.571Å c: 290.255Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.245 0.244 0.274
Expression system: Escherichia coli

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