› 3hzm

X-ray diffraction
1.8Å resolution

Crystal structure of S73-2 antibody in complex with antigen Kdo

Released:
DOI: 10.2210/pdb3hzm/pdb
PDB entry 3hzm coloured by chain, front view.
PDB entry 3hzm coloured by chain, side view.
PDB entry 3hzm coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition.
Brooks CL, Müller-Loennies S, Borisova SN, Brade L, Kosma P, Hirama T, Mackenzie CR, Brade H, Evans SV
Biochemistry 49 570-81 (2010)
PMID: 20000757

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213275 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
S73-2 Fab (IgG1k) light chain Chain: A
Molecule details ›
Chain: A
Length: 219 amino acids
Theoretical weight: 24.21 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
S73-2 Fab (IgG1k) heavy chain Chain: B
Molecule details ›
Chain: B
Length: 225 amino acids
Theoretical weight: 24.35 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
Ligand MG 3 x MG
Ligand ZN 1 x ZN
Ligand KDO 1 x KDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-002+
Spacegroup: P212121
Unit cell:
a: 46Å b: 81.8Å c: 127.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.207 0.249

Quick links

Citations

2 review citations

Antibody recognition of carbohydrate epitopes†.
Haji-Ghassemi et al. (2015)
1 more

2 mentions without citation

Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition.
Brooks et al. (2010)
1 more