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› 3hzu

X-ray diffraction
2.1Å resolution

Crystal structure of probable thiosulfate sulfurtransferase SSEA (rhodanese) from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb3hzu/pdb
Model geometry
Fit model/data
PDB entry 3hzu coloured by chain, front view.
PDB entry 3hzu coloured by chain, side view.
PDB entry 3hzu coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Mycobacterium thermoresistibile as a source of thermostable orthologs of Mycobacterium tuberculosis proteins.
Edwards TE, Liao R, Phan I, Myler PJ, Grundner C
Protein Sci 21 1093-6 (2012)
PMID: 22544630

Function and Biology Details

Reaction catalysed: 
thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H(+).
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161547 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative thiosulfate sulfurtransferase SseA Chain: A
Molecule details ›
Chain: A
Length: 318 amino acids
Theoretical weight: 35.65 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WHF7 (Residues: 1-297; Coverage: 100%)
Gene names: MTCY71.23, Rv3283, sseA
Sequence domains: Rhodanese-like domain
Structure domains: Rhodanese-like domain

Ligands and Environments

2 bound ligands:
Ligand GOL 1 x GOL
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P21212
Unit cell:
a: 90.73Å b: 88.327Å c: 36.794Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.205 0.249
Expression system: Escherichia coli

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Citations

9 citation in other articles

Combining functional and structural genomics to sample the essential Burkholderia structome.
Baugh et al. (2013)
8 more

2 mentions without citation

Disclosure of selective advantages in the "modern" sublineage of the Mycobacterium tuberculosis Beijing genotype family by quantitative proteomics.
de Keijzer et al. (2014)
1 more