› 3i7j

X-ray diffraction
2.2Å resolution

Crystal Structure of a beta-lactamase (Mb2281c) from Mycobacterium bovis, Northeast Structural Genomics Consortium Target MbR246

Released:
DOI: 10.2210/pdb3i7j/pdb
PDB entry 3i7j coloured by chain, front view.
PDB entry 3i7j coloured by chain, side view.
PDB entry 3i7j coloured by chain, top view.
Source organism: Mycobacterium tuberculosis variant bovis
Entry authors: Forouhar F, Lew S, Seetharaman J, Sahdev S, Xiao R, Ciccosanti C, Wang H, Everett JK, Nair R, Acton TB, Rost B, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163646 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
beta-lactamase Mb2281c Chains: A, B
Molecule details ›
Chains: A, B
Length: 280 amino acids
Theoretical weight: 29.71 KDa
Source organism: Mycobacterium tuberculosis variant bovis
Expression system: Escherichia coli BL21(DE3)
Structure domains: DD-peptidase/beta-lactamase superfamily

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 65.097Å b: 97.834Å c: 114.807Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.233
Expression system: Escherichia coli BL21(DE3)

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