3i90

X-ray diffraction
2Å resolution

Crystal structure of human chromobox homolog 6 (CBX6) with H3K27 peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-131945 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Chromobox protein homolog 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 51 amino acids
Theoretical weight: 6.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95503 (Residues: 9-59; Coverage: 12%)
Gene name: CBX6
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
H3K27 peptide Chains: C, D
Molecule details ›
Chains: C, D
Length: 11 amino acids
Theoretical weight: 1.19 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ DW
Spacegroup: P6522
Unit cell:
a: 53.421Å b: 53.421Å c: 227.778Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.254 0.252 0.3
Expression systems:
  • Escherichia coli
  • Not provided