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› 3iah

X-ray diffraction
1.83Å resolution

Crystal Structure of Short Chain Dehydrogenase (yciK) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 in Complex with NADP and Acetate.

Released:
DOI: 10.2210/pdb3iah/pdb
Model geometry
Fit model/data
PDB entry 3iah coloured by chain, front view.
PDB entry 3iah coloured by chain, side view.
PDB entry 3iah coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Entry authors: Minasov G, Halavaty A, Skarina T, Onopriyenko O, Peterson SN, Savchenko A, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181414 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxoacyl-(Acyl carrier protein) reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 256 amino acids
Theoretical weight: 28.85 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7CQG2 (Residues: 1-253; Coverage: 100%)
Gene names: STM1717, yciK
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

4 bound ligands:
Ligand NAP 2 x NAP
Ligand ACT 3 x ACT
Ligand EOH 2 x EOH
Ligand CL 1 x CL
1 modified residue:
Ligand MSE 20 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: C2
Unit cell:
a: 158.664Å b: 43.302Å c: 71.916Å
α: 90° β: 93.24° γ: 90°
R-values:
R R work R free
0.145 0.143 0.176
Expression system: Escherichia coli BL21(DE3)

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