› 3ila

X-ray diffraction
2.9Å resolution

Crystal structure of rabbit ryanodine receptor 1 N-terminal domain (9-205)

Released:
DOI: 10.2210/pdb3ila/pdb
PDB entry 3ila coloured by chain, front view.
PDB entry 3ila coloured by chain, side view.
PDB entry 3ila coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations.
Lobo PA, Van Petegem F
Structure 17 1505-14 (2009)
PMID: 19913485

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145900 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ryanodine receptor 1 Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 197 amino acids
Theoretical weight: 21.77 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P11716 (Residues: 9-205; Coverage: 4%)
Gene name: RYR1
Sequence domains: Inositol 1,4,5-trisphosphate/ryanodine receptor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21
Unit cell:
a: 70.734Å b: 155.705Å c: 81.613Å
α: 90° β: 110.63° γ: 90°
R-values:
R R work R free
0.277 0.274 0.32
Expression system: Escherichia coli

Quick links

Citations

22 review citations

Inherited dysfunction of sarcoplasmic reticulum Ca2+ handling and arrhythmogenesis.
Priori et al. (2011)
21 more

3 mentions without citation

Ryanodine receptors: structure, expression, molecular details, and function in calcium release.
Lanner et al. (2010)
2 more