› 3iox

X-ray diffraction
1.8Å resolution

Crystal Structure of A3VP1 of AgI/II of Streptococcus mutans

Released:
DOI: 10.2210/pdb3iox/pdb
PDB entry 3iox coloured by chain, front view.
PDB entry 3iox coloured by chain, side view.
PDB entry 3iox coloured by chain, top view.
Source organism: Streptococcus mutans
Primary publication:
Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of alpha- and PPII-helices.
Larson MR, Rajashankar KR, Patel MH, Robinette RA, Crowley PJ, Michalek S, Brady LJ, Deivanayagam C
Proc Natl Acad Sci U S A 107 5983-8 (2010)
PMID: 20231452

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108780 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gram-positive cocci surface proteins LPxTG domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 497 amino acids
Theoretical weight: 54.45 KDa
Source organism: Streptococcus mutans
Expression system: Escherichia coli
UniProt:
  • Canonical: A8R5D9 (Residues: 386-874; Coverage: 32%)
Gene name: pa
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand PMS 1 x PMS
Ligand SO3 2 x SO3
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21212
Unit cell:
a: 70.725Å b: 153.057Å c: 49.677Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.19 0.228
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Amyloid Structures as Biofilm Matrix Scaffolds.
Taglialegna et al. (2016)
8 more

8 mentions without citation

Polyproline and triple helix motifs in host-pathogen recognition.
Berisio et al. (2012)
7 more