› 3iq2

X-ray diffraction
1.7Å resolution

Human sorting nexin 7, phox homology (PX) domain

Released:
DOI: 10.2210/pdb3iq2/pdb
PDB entry 3iq2 coloured by chain, front view.
PDB entry 3iq2 coloured by chain, side view.
PDB entry 3iq2 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Karlberg T, Wisniewska M, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson A, Johansson I, Kallas A, Kotenyova T, Kotzsch A, Kraulis P, Nielsen TK, Moche M, Nordlund P, Nyman T, Persson C, Roos AK, Schutz P, Siponen MI, Thorsell AG, Tresaugues L, Van Den Berg S, Weigelt J, Welin M, Schuler H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193995 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 16.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UNH6 (Residues: 25-154; Coverage: 34%)
Gene name: SNX7
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

2 bound ligands:
Ligand GOL 2 x GOL
Ligand SO4 11 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-2
Spacegroup: P32
Unit cell:
a: 57.3Å b: 57.3Å c: 97.1Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.166 0.165 0.2
Expression system: Escherichia coli BL21(DE3)

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