› 3iug

X-ray diffraction
1.77Å resolution

Crystal structure of the RhoGAP domain of RICS

Released:
DOI: 10.2210/pdb3iug/pdb
PDB entry 3iug coloured by chain, front view.
PDB entry 3iug coloured by chain, side view.
PDB entry 3iug coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Nedyalkova L, Tempel W, Tong Y, Li Y, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108270 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho GTPase-activating protein 32 Chains: A, B
Molecule details ›
Chains: A, B
Length: 229 amino acids
Theoretical weight: 26.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: A7KAX9 (Residues: 367-577; Coverage: 10%)
Gene names: ARHGAP32, GRIT, KIAA0712, RICS
Sequence domains: RhoGAP domain
Structure domains: Rho GTPase activation protein

Ligands and Environments

1 bound ligand:
Ligand UNX 11 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: P21212
Unit cell:
a: 102.264Å b: 117.369Å c: 37.717Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.199 0.245
Expression system: Escherichia coli

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