› 3jcf

Electron Microscopy
3.8Å resolution

Cryo-EM structure of the magnesium channel CorA in the closed symmetric magnesium-bound state

Released:
DOI: 10.2210/pdb3jcf/pdb
PDB entry 3jcf coloured by chain, front view.
PDB entry 3jcf coloured by chain, side view.
PDB entry 3jcf coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Matthies D, Dalmas O, Borgnia MJ, Dominik PK, Merk A, Rao P, Reddy BG, Islam S, Bartesaghi A, Perozo E, Subramaniam S
Cell 164 747-56 (2016)
PMID: 26871634
Related structures: EMD-6551

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cobalt/magnesium transport protein CorA Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 351 amino acids
Theoretical weight: 41.5 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9WZ31 (Residues: 1-351; Coverage: 100%)
Gene names: TM_0561, corA
Sequence domains: CorA-like Mg2+ transporter protein
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand MG 13 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-6551
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

18 review citations

Nanodiscs for structural and functional studies of membrane proteins.
Denisov et al. (2016)
17 more

14 mentions without citation

Structural and functional comparison of magnesium transporters throughout evolution.
Franken et al. (2022)
13 more