› 3jrp

X-ray diffraction
2.6Å resolution

SEC13 with NUP145C (AA109-179) insertion blade

Released:
DOI: 10.2210/pdb3jrp/pdb
PDB entry 3jrp coloured by chain, front view.
PDB entry 3jrp coloured by chain, side view.
PDB entry 3jrp coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice.
Brohawn SG, Schwartz TU
Nat Struct Mol Biol 16 1173-7 (2009)
PMID: 19855394

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155986 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin NUP145C; Protein transport protein SEC13 Chain: A
Molecule details ›
Chain: A
Length: 379 amino acids
Theoretical weight: 41.7 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: Q04491 (Residues: 1-297; Coverage: 100%)
  • Canonical: P49687 (Residues: 714-784; Coverage: 5%)
Gene names: ANU3, L8167.4, NUP145, RAT10, SEC13, YGL092W, YLR208W
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21212
Unit cell:
a: 68.28Å b: 93.878Å c: 55.047Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.217 0.254
Expression system: Escherichia coli

Quick links

Citations

16 review citations

The structure of the nuclear pore complex.
Hoelz et al. (2011)
15 more

4 mentions without citation

Membrane-coating lattice scaffolds in the nuclear pore and vesicle coats: commonalities, differences, challenges.
Leksa et al. (2010)
3 more