› 3jsc

X-ray diffraction
1.5Å resolution

CcdBVfi-FormI-pH7.0

Released:
DOI: 10.2210/pdb3jsc/pdb
PDB entry 3jsc coloured by chain, front view.
PDB entry 3jsc coloured by chain, side view.
PDB entry 3jsc coloured by chain, top view.
Source organism: Aliivibrio fischeri
Primary publication:
Structural and thermodynamic characterization of Vibrio fischeri CcdB.
De Jonge N, Hohlweg W, Garcia-Pino A, Respondek M, Buts L, Haesaerts S, Lah J, Zangger K, Loris R
J Biol Chem 285 5606-13 (2010)
PMID: 19959472

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183017 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxin CcdB Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.88 KDa
Source organism: Aliivibrio fischeri
Expression system: Escherichia coli
UniProt:
  • Canonical: Q84B82 (Residues: 1-105; Coverage: 100%)
Gene name: ccdB
Sequence domains: CcdB protein
Structure domains: SH3 type barrels.

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: I213
Unit cell:
a: 84.487Å b: 84.487Å c: 84.487Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.172 0.202
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Toxin-antitoxin systems in bacteria and archaea.
Yamaguchi et al. (2011)
2 more

6 mentions without citation

Structure, Biology, and Therapeutic Application of Toxin-Antitoxin Systems in Pathogenic Bacteria.
Lee et al. (2016)
5 more