› 3jtw

X-ray diffraction
1.9Å resolution

Crystal structure of Putative dihydrofolate reductase (YP_805003.1) from PEDIOCOCCUS PENTOSACEUS ATCC 25745 at 1.90 A resolution

Released:
DOI: 10.2210/pdb3jtw/pdb
PDB entry 3jtw coloured by chain, front view.
PDB entry 3jtw coloured by chain, side view.
PDB entry 3jtw coloured by chain, top view.
Source organism: Pediococcus pentosaceus ATCC 25745
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169963 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bacterial bifunctional deaminase-reductase C-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 178 amino acids
Theoretical weight: 20.74 KDa
Source organism: Pediococcus pentosaceus ATCC 25745
Expression system: Escherichia coli
UniProt:
  • Canonical: Q03E11 (Residues: 1-177; Coverage: 100%)
Gene name: PEPE_1533
Sequence domains: RibD C-terminal domain
Structure domains: Dihydrofolate Reductase, subunit A

Ligands and Environments

3 bound ligands:
Ligand UNL 1 x UNL
Ligand SO4 4 x SO4
Ligand EDO 1 x EDO
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21212
Unit cell:
a: 69.759Å b: 83.314Å c: 65.059Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.225
Expression system: Escherichia coli

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