› 3jui

X-ray diffraction
2Å resolution

Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit

Released:
DOI: 10.2210/pdb3jui/pdb
PDB entry 3jui coloured by chain, front view.
PDB entry 3jui coloured by chain, side view.
PDB entry 3jui coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wei J, Xu H, Zhang C, Wang M, Gao F, Gong W

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171556 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Translation initiation factor eIF2B subunit epsilon Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 21.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13144 (Residues: 548-721; Coverage: 24%)
Gene names: EIF2B5, EIF2BE
Sequence domains: eIF4-gamma/eIF5/eIF2-epsilon
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: C2221
Unit cell:
a: 46.537Å b: 66.082Å c: 136.128Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.211 0.279
Expression system: Escherichia coli

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