› 3jv3

X-ray diffraction
2.4Å resolution

Structure of SH3E-DH unit of murine intersectin-1L

Released:
DOI: 10.2210/pdb3jv3/pdb
PDB entry 3jv3 coloured by chain, front view.
PDB entry 3jv3 coloured by chain, side view.
PDB entry 3jv3 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The minimal autoinhibited unit of the guanine nucleotide exchange factor intersectin.
Ahmad KF, Lim WA
PLoS One 5 e11291 (2010)
PMID: 20585582

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195528 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Intersectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 283 amino acids
Theoretical weight: 32.72 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Z0R4 (Residues: 1151-1431; Coverage: 16%)
Gene names: Ese1, Itsn, Itsn1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P3221
Unit cell:
a: 67.044Å b: 67.044Å c: 341.818Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.25 0.248 0.287
Expression system: Escherichia coli

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Citations

5 review citations

Regulation of small GTPases by GEFs, GAPs, and GDIs.
Cherfils et al. (2013)
4 more

3 mentions without citation

The minimal autoinhibited unit of the guanine nucleotide exchange factor intersectin.
Ahmad et al. (2010)
2 more