› 3k5s

X-ray diffraction
2.9Å resolution

Crystal structure of chicken T-cadherin EC1 EC2

Released:
DOI: 10.2210/pdb3k5s/pdb
PDB entry 3k5s coloured by chain, front view.
PDB entry 3k5s coloured by chain, side view.
PDB entry 3k5s coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
T-cadherin structures reveal a novel adhesive binding mechanism.
Ciatto C, Bahna F, Zampieri N, VanSteenhouse HC, Katsamba PS, Ahlsen G, Harrison OJ, Brasch J, Jin X, Posy S, Vendome J, Ranscht B, Jessell TM, Honig B, Shapiro L
Nat Struct Mol Biol 17 339-47 (2010)
PMID: 20190755

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152544 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadherin-13 Chains: A, B
Molecule details ›
Chains: A, B
Length: 217 amino acids
Theoretical weight: 23.75 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P33150 (Residues: 140-355; Coverage: 31%)
Gene name: CDH13
Sequence domains: Cadherin domain
Structure domains: Cadherins

Ligands and Environments

1 bound ligand:
Ligand CA 6 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 55.804Å b: 79.188Å c: 105.162Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.213 0.294
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Thinking outside the cell: how cadherins drive adhesion.
Brasch et al. (2012)
13 more

2 mentions without citation

Structural origins of clustered protocadherin-mediated neuronal barcoding.
Rubinstein et al. (2017)
1 more