› 3k6d

X-ray diffraction
1.8Å resolution

Crystal structure of Xenopus laevis T-cadherin EC1

Released:
DOI: 10.2210/pdb3k6d/pdb
PDB entry 3k6d coloured by chain, front view.
PDB entry 3k6d coloured by chain, side view.
PDB entry 3k6d coloured by chain, top view.
Source organism: Xenopus laevis
Primary publication:
T-cadherin structures reveal a novel adhesive binding mechanism.
Ciatto C, Bahna F, Zampieri N, VanSteenhouse HC, Katsamba PS, Ahlsen G, Harrison OJ, Brasch J, Jin X, Posy S, Vendome J, Ranscht B, Jessell TM, Honig B, Shapiro L
Nat Struct Mol Biol 17 339-47 (2010)
PMID: 20190755

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178503 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadherin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.8 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5XHE3 (Residues: 136-233; Coverage: 14%)
Gene names: LOC495024, cdh13, cdh13.L
Sequence domains: Cadherin domain
Structure domains: Cadherins

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: I4122
Unit cell:
a: 78.91Å b: 78.91Å c: 62.577Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.227 0.285
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Thinking outside the cell: how cadherins drive adhesion.
Brasch et al. (2012)
14 more

1 mention without citation

T-cadherin structures reveal a novel adhesive binding mechanism.
Ciatto et al. (2010)