3k6g

X-ray diffraction
1.95Å resolution

Crystal structure of Rap1 and TRF2 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-172319 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Telomeric repeat-binding factor 2-interacting protein 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 111 amino acids
Theoretical weight: 12.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NYB0 (Residues: 303-399; Coverage: 24%)
Gene names: DRIP5, PP8000, RAP1, TERF2IP
Sequence domains: TRF2-interacting telomeric protein/Rap1 - C terminal domain
Telomeric repeat-binding factor 2 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 42 amino acids
Theoretical weight: 4.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15554 (Residues: 317-358; Coverage: 8%)
Gene names: TERF2, TRBF2, TRF2
Sequence domains: Telomeric repeat-binding factor 2 Rap1-binding motif

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P212121
Unit cell:
a: 42.568Å b: 72.105Å c: 150.993Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.236
Expression system: Escherichia coli