› 3k8g

X-ray diffraction
1.95Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130595 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein TP0453 Chains: A, B
Molecule details ›
Chains: A, B
Length: 262 amino acids
Theoretical weight: 29.15 KDa
Source organism: Treponema pallidum
Expression system: Escherichia coli
UniProt:
  • Canonical: O67998 (Residues: 27-287; Coverage: 99%)
Gene names: TPANIC_0453, TP_0453
Sequence domains: Outer membrane-associated lipoprotein TP0453

Ligands and Environments

1 bound ligand:
Ligand MPD 4 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P21212
Unit cell:
a: 87.747Å b: 159.872Å c: 44.527Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.215 0.254
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Syphilis.
Peeling et al. (2017)
3 more

1 mention without citation

The transition from closed to open conformation of Treponema pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices.
Luthra et al. (2011)