› 3kma

X-ray diffraction
1.6Å resolution

Crystal Structure of vSET under Condition A

Released:
DOI: 10.2210/pdb3kma/pdb
PDB entry 3kma coloured by chain, front view.
PDB entry 3kma coloured by chain, side view.
PDB entry 3kma coloured by chain, top view.
Source organism: Paramecium bursaria Chlorella virus 1
Primary publication:
Dimerization of a viral SET protein endows its function.
Wei H, Zhou MM
Proc Natl Acad Sci U S A 107 18433-8 (2010)
PMID: 20937900

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128784 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SET domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 119 amino acids
Theoretical weight: 13.61 KDa
Source organism: Paramecium bursaria Chlorella virus 1
UniProt:
  • Canonical: O41094 (Residues: 1-119; Coverage: 100%)
Gene name: A612L
Sequence domains: SET domain
Structure domains: SET domain

Ligands and Environments

3 bound ligands:
Ligand GOL 2 x GOL
Ligand SO4 2 x SO4
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P3221
Unit cell:
a: 60.403Å b: 60.403Å c: 102.417Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.25 0.234 0.264

Quick links

Citations

3 review citations

EZH2: biology, disease, and structure-based drug discovery.
Tan et al. (2014)
2 more

1 mention without citation

Dimerization of a viral SET protein endows its function.
Wei et al. (2010)