› 3kmj

X-ray diffraction
1.85Å resolution

Crystal structure of vSET under condition B

Released:
DOI: 10.2210/pdb3kmj/pdb
PDB entry 3kmj coloured by chain, front view.
PDB entry 3kmj coloured by chain, side view.
PDB entry 3kmj coloured by chain, top view.
Source organism: Paramecium bursaria Chlorella virus 1
Primary publication:
Dimerization of a viral SET protein endows its function.
Wei H, Zhou MM
Proc Natl Acad Sci U S A 107 18433-8 (2010)
PMID: 20937900

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128784 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SET domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.61 KDa
Source organism: Paramecium bursaria Chlorella virus 1
UniProt:
  • Canonical: O41094 (Residues: 1-119; Coverage: 100%)
Gene name: A612L
Sequence domains: SET domain
Structure domains: SET domain

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P3112
Unit cell:
a: 59.18Å b: 59.18Å c: 53.72Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.26 0.234 0.281

Quick links

Citations

3 review citations

EZH2: biology, disease, and structure-based drug discovery.
Tan et al. (2014)
2 more

1 mention without citation

Dimerization of a viral SET protein endows its function.
Wei et al. (2010)