› 3kom

X-ray diffraction
1.6Å resolution

Crystal structure of apo transketolase from Francisella tularensis

Released:
DOI: 10.2210/pdb3kom/pdb
PDB entry 3kom coloured by chain, front view.
PDB entry 3kom coloured by chain, side view.
PDB entry 3kom coloured by chain, top view.
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Entry authors: Anderson SM, Wawrzak Z, Skarina T, Gordon E, Kwon K, Savchenko A, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177658 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transketolase Chains: A, B
Molecule details ›
Chains: A, B
Length: 663 amino acids
Theoretical weight: 74.41 KDa
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5NF74 (Residues: 1-663; Coverage: 100%)
Gene names: FTT_1369c, tktA
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
2 modified residues:
Ligand MSE 42 x MSE
Ligand OCS 2 x OCS

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 86.49Å b: 109.29Å c: 128.56Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.163 0.199
Expression system: Escherichia coli

Quick links