› 3kvt

X-ray diffraction
2Å resolution

TETRAMERIZATION DOMAIN FROM AKV3.1 (SHAW-SUBFAMILY) VOLTAGE-GATED POTASSIUM CHANNEL

Released:
DOI: 10.2210/pdb3kvt/pdb
PDB entry 3kvt coloured by chain, front view.
PDB entry 3kvt coloured by chain, side view.
PDB entry 3kvt coloured by chain, top view.
Source organism: Aplysia californica
Primary publication:
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels.
Bixby KA, Nanao MH, Shen NV, Kreusch A, Bellamy H, Pfaffinger PJ, Choe S
Nat Struct Biol 6 38-43 (1999)
PMID: 9886290

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131229 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BTB domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 115 amino acids
Theoretical weight: 13.39 KDa
Source organism: Aplysia californica
Expression system: Escherichia coli
UniProt:
  • Canonical: O76457 (Residues: 7-120; Coverage: 22%)
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: I422
Unit cell:
a: 67.191Å b: 67.191Å c: 138.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.238
Expression system: Escherichia coli

Quick links

Citations

24 review citations

Molecular physiology and modulation of somatodendritic A-type potassium channels.
Jerng et al. (2004)
23 more

5 mentions without citation

Pentameric assembly of potassium channel tetramerization domain-containing protein 5.
Dementieva et al. (2009)
4 more