› 3kxs

X-ray diffraction
2.25Å resolution

Crystal structure of HBV capsid mutant dimer (oxy form), strain adyw

Released:
DOI: 10.2210/pdb3kxs/pdb
PDB entry 3kxs coloured by chain, front view.
PDB entry 3kxs coloured by chain, side view.
PDB entry 3kxs coloured by chain, top view.
Source organism: Hepatitis B virus subtype adyw
Primary publication:
Conformational changes in the hepatitis B virus core protein are consistent with a role for allostery in virus assembly.
Packianathan C, Katen SP, Dann CE, Zlotnick A
J Virol 84 1607-15 (2010)
PMID: 19939922

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136616 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 143 amino acids
Theoretical weight: 16.07 KDa
Source organism: Hepatitis B virus subtype adyw
Expression system: Escherichia coli
UniProt:
  • Canonical: P03147 (Residues: 1-143; Coverage: 78%)
Gene name: C
Sequence domains: Hepatitis core antigen
Structure domains: Viral capsid, core domain supefamily, Hepatitis B virus

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P31
Unit cell:
a: 104.162Å b: 104.162Å c: 86.917Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.217 0.264
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Native ion mobility-mass spectrometry and related methods in structural biology.
Konijnenberg et al. (2013)
10 more

13 mentions without citation

Core protein: A pleiotropic keystone in the HBV lifecycle.
Zlotnick et al. (2015)
12 more