› 3l30

X-ray diffraction
2.4Å resolution

Crystal structure of porcine pancreatic phospholipase A2 complexed with dihydroxyberberine

Released:
DOI: 10.2210/pdb3l30/pdb
PDB entry 3l30 coloured by chain, front view.
PDB entry 3l30 coloured by chain, side view.
PDB entry 3l30 coloured by chain, top view.
Source organism: Sus scrofa
Entry authors: Naveen C, Prasanth GK, Abhilash J, Pradeep M, Ponnuraj K, Sadasivan C, Haridas M

Function and Biology Details

Reaction catalysed: 
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132748 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phospholipase A2, major isoenzyme Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 14.01 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P00592 (Residues: 23-146; Coverage: 95%)
Gene name: PLA2G1B
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain

Ligands and Environments

3 bound ligands:
Ligand CA 1 x CA
Ligand CL 2 x CL
Ligand DBW 1 x DBW
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P3121
Unit cell:
a: 68.88Å b: 68.88Å c: 70.16Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.163 0.163 0.24

Quick links