› 3l7h

X-ray diffraction
1.95Å resolution

Insights into dynein assembly from a dynein intermediate chain light chain Roadblock structure

Released:
DOI: 10.2210/pdb3l7h/pdb
PDB entry 3l7h coloured by chain, front view.
PDB entry 3l7h coloured by chain, side view.
PDB entry 3l7h coloured by chain, top view.
Source organism: Drosophila melanogaster
Entry authors: Hall J, Karplus PA, Barbar E

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181594 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dynein light chain roadblock Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 97 amino acids
Theoretical weight: 10.84 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7KMS3 (Residues: 1-97; Coverage: 100%)
Gene names: CG10751, DLC, Dmel\CG10751, Dmel_CG10751, LC7, l(2)k10408, robl, roblk
Sequence domains: Roadblock/LC7 domain
Structure domains: Dynein light chain 2a, cytoplasmic

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 56.218Å b: 58.693Å c: 65.095Å
α: 90° β: 101.8° γ: 90°
R-values:
R R work R free
0.199 0.193 0.254
Expression system: Escherichia coli BL21(DE3)

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